#537: Datastar: Modern web dev, simplified

21.02.2026 • 01:16:37

You love building web apps with Python, and HTMX got you excited about the hypermedia approach -- let the server drive the HTML, skip the JavaScript b...

#536: Fly inside FastAPI Cloud

10.02.2026 • 01:07:00

You've built your FastAPI app, it's running great locally, and now you want to share it with the world. But then reality hits -- containers, load bala...

#535: PyView: Real-time Python Web Apps

23.01.2026 • 01:07:56

Building on the web is like working with the perfect clay. It’s malleable and can become almost anything. But too often, frameworks try to hide the we...

#534: diskcache: Your secret Python perf weapon

13.01.2026 • 01:14:00

Your cloud SSD is sitting there, bored, and it would like a job. Today we’re putting it to work with DiskCache, a simple, practical cache built on SQL...

#533: Web Frameworks in Prod by Their Creators

05.01.2026 • 01:01:58

Today on Talk Python, the creators behind FastAPI, Flask, Django, Quart, and Litestar get practical about running apps based on their framework in pro...

#532: 2025 Python Year in Review

29.12.2025 • 01:18:32

Python in 2025 is in a delightfully refreshing place: the GIL's days are numbered, packaging is getting sharper tools, and the type checkers are multi...

#531: Talk Python in Production

18.12.2025 • 01:21:13

Have you ever thought about getting your small product into production, but are worried about the cost of the big cloud providers? Or maybe you think ...

#530: anywidget: Jupyter Widgets made easy

13.12.2025 • 01:11:21

For years, building interactive widgets in Python notebooks meant wrestling with toolchains, platform quirks, and a mountain of JavaScript machinery. ...

#529: Computer Science from Scratch

03.12.2025 • 01:17:00

A lot of people building software today never took the traditional CS path. They arrived through curiosity, a job that needed automating, or a late-ni...

#528: Python apps with LLM building blocks

30.11.2025 • 01:16:46

In this episode, I’m talking with Vincent Warmerdam about treating LLMs as just another API in your Python app, with clear boundaries, small focused e...