This Startup Wants To Catch Cancer Before It Spreads
1 in 11 babies born in America this year will be screened by a genetic test that didn't exist a decade ago.Biotech startup BillionToOne turned a simpl...
This Startup Secretly Detects Fraud For Fortune 500s
In this episode of Founder Firesides, YC Managing Partner Jared Friedman talks to Karine Mellata, co-founder of Variance (W23), who is coming out of s...
How François Chollet Is Building A New Path To AGI
François Chollet has spent years asking a different question than most of the AI world. Instead of scaling what already works, he’s trying to understa...
Inside The Startup Reinventing America’s Trillion Dollar Chemical Industry
Solugen is reinventing the trillion-dollar chemical manufacturing industry by combining biology and chemistry in a new way. In this episode of Hard Te...
Building A Global AI Startup From India
In this episode of The Lightcone, we talk with Mukund and Madhav Jha, the founders of Emergent - an AI platform that lets anyone build and ship produc...
The Future Of Brain-Computer Interfaces with Science's Max Hodak
YC alum Max Hodak is the co-founder of Neuralink and founder of Science, a company building brain-computer interfaces that can restore sight.Science h...
How To Avoid AI Design Slop
As no-code design tools become more common, so do the pitfalls. You know what they look like - the purple gradients, annoying hover effects, sections ...
The Fastest Path To Super Intelligence
Poetiq is a new startup founded by former DeepMind researchers that recently achieved a major jump on the ARC-AGI and Humanity's Last Exam benchmark b...
The AI Agent Economy Is Here
With the takeoff of OpenClaw and MoltBook, a new agent-driven economy is taking shape. In this episode of the Lightcone, we took a look at the explos...
Inside Claude Code With Its Creator Boris Cherny
A very special guest on this episode of the Lightcone! Boris Cherny, the creator of Claude Code, sits down to share the incredible journey of developi...